Consultant (ISSN:0010-7069) is a monthly peer-reviewed scopus-indexed journal from 1987 to upto now. The publisher of this journal is Journal of Cliggott Publishing Co. Consultant (ISSN:0010-7069) is committed to gathering and disseminating excellent research achievements.The journal welcomes all kinds of research/review/abstract papers regarding General Medicine subjects including Medicine, pharmacy, biochemistry, psychology, Public health, and so on.
Smoking among young people remains a major public health concern in Asia. This cross-sectional study examined the barriers and determinants of smoking cessation among young tobacco users in Pakistan, Nepal, and Bangladesh. A total of 425 participants aged 18–30 years were recruited using a stratified multistage sampling technique. Data were collected through a structured self-administered questionnaire covering socio-demographic characteristics, tobacco use patterns, nicotine dependence, quit attempts, barriers, facilitators, and access to cessation services. Descriptive statistics, bivariat
Read MoreFolate metabolism plays a critical role in DNA synthesis, repair, and methylation, which are essential for reproductive function and fetal development. Polymorphisms in folate-cycle genes, particularly MTHFR and MTRR, may impair enzyme activity, leading to elevated homocysteine levels and adverse reproductive and neonatal outcomes. This study aimed to evaluate the association of these gene polymorphisms with infertility, pregnancy complications, and congenital anomalies in newborns. A case–control study was conducted including 360 participants divided into three groups: women with infertilit
Read MoreType 2 diabetes mellitus (T2DM) is a chronic metabolic disorder requiring effective glycemic management to prevent complications. Metformin and sulfonylureas are widely used oral hypoglycemic agents, but their comparative effectiveness in real-world clinical settings remains an area of interest. The aim of study is to compare the impact of metformin and sulfonylureas on glycemic control, weight change, and hypoglycemia incidence among patients with T2DM. A retrospective quantitative study was conducted using medical records of 308 adult patients with T2DM, including 154 patients receiving metf
Read MoreAnatomical variations of the coronary arteries, including differences in dominance patterns, anomalous origins, and myocardial bridging, can significantly influence myocardial perfusion and clinical outcomes in acute coronary syndromes. However, the prognostic implications of these variants in myocardial infarction (MI) remain underexplored. This study aimed to evaluate the prevalence of coronary artery anatomical variations in MI patients and assess their physiological relevance to infarct location and in-hospital outcomes. A cross-sectional observational study was conducted on 92 patients ad
Read MoreNon-valvular atrial fibrillation (NVAF) is a common cardiac arrhythmia that increases the risk of thromboembolic events, especially during the perioperative period. Anticoagulation therapy with either novel oral anticoagulants (NOACs) or warfarin is essential for stroke prevention; however, managing these therapies around the time of surgery poses a clinical challenge due to the dual risks of bleeding and thrombosis. While NOACs have gained widespread use, their comparative safety and efficacy to warfarin in surgical settings remain inadequately defined. This study aimed to compare the effecti
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